Anti-14-3-3 beta Mouse Monoclonal Antibody [clone: 60C10]

Toimittaja: AbFrontier
Anti-14-3-3 beta Mouse Monoclonal Antibody [clone: 60C10]
14-3-3, a family of acidic and soluble proteins, highly conserved in amino acid sequences from yeast to mammals, is expressed in all eukaryotic cells. Seven isoforms(β, γ, ε, η, ζ, σ and τ/θ) encoded by seven distinct genes are identified in mammals and forms homo- and hetero- dimeric cup-shaped structures. As 14-3-3 is interacted with more than 100 binding partners, it regulates key proteins involved in various biological processes such as signal trans-duction, cell cycle, transcriptional control, cell proliferation, apoptosis, and ion channel physiology. Most 14-3-3 requires phosphorylation of serine or threonine residues in the target sequence. This protein is abundantly expressed in the brain and has been detected in the cerebrospinal fluid of patients with different neurological disorders.

Western Blot: 0.5 ?g/ml;

Type: Primary
Antigen: 14-3-3 beta (14-3-3 beta)
Clonality: Monoclonal
Clone: 60C10
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG2b Kappa
Reactivity: Human, Mouse, Rat
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