Anti-TNFRSF18 Rat Monoclonal Antibody [clone: DTA-1]

Toimittaja: Tonbo Biosciences
40-5874-U100EA 172 EUR
Anti-TNFRSF18 Rat Monoclonal Antibody [clone: DTA-1]
The DTA-1 antibody reacts with mouse CD357, also known as GITR or AITR (in humans), a 66-70 kDa member of the Tumor Necrosis Factor superfamily (TNFRSF18). GITR is primarily found on T cells, and its function may vary depending on the T cell type where it is expressed. GITR is upregulated on activated T cells where it provides co-stimulation, yet GITR may promote the inhibition of CD4+ CD25+ Treg cells, where it is expressed at high levels. GITR ligand (GITRL) is found on B cells, macrophages, dendritic and endothelial cells, and is implicated in regulating both innate and adaptive immune responses.

Type: Primary
Antigen: TNFRSF18 (tumor necrosis factor receptor superfamily, member 18)
Clonality: monoclonal
Clone: DTA-1
Conjugation: unconjugated
Host: Rat
Isotype: IgG2b
Reactivity: Mouse
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