Anti-CD3E Armenian Hamster Monoclonal Antibody [clone: 145-2C11]

Toimittaja: Tonbo Biosciences
70-0031-U500EA 60.3 EUR
70-0031-U500 70-0031-U100 70-0031-M001
Anti-CD3E Armenian Hamster Monoclonal Antibody [clone: 145-2C11]
Vasta-aineet
The 145-2C11 antibody is specific for mouse CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

Type: Primary
Antigen: CD3E (CD3e molecule, epsilon (CD3-TCR complex))
Clonality: monoclonal
Clone: 145-2C11
Conjugation: unconjugated
Epitope:
Host: Armenian Hamster
Isotype: IgG
Reactivity: Mouse
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