Anti-proNGF Sheep Polyclonal Antibody

Toimittaja: Biosensis
BSENS-080-100EA 302 EUR
Anti-proNGF Sheep Polyclonal Antibody
Nerve growth factor (NGF) is synthesized as a precursor (proNGF) which may be released and have physiological functions to cause cell death. It binds neurotrophin receptor p75 and sortilin and may also be important for the development of nervous system. proNGF is synthesized in target tissues and glia, transported retrogradely and may be released. This antibody is raised in sheep to detect the prodomain of NGF not the mature peptide.

The specificity of this antibody has been confirmed by WB. It does NOT crossreact with proBDNF, proNT-3 or mature NGF.
Application Information:
IHC, Immunofluorescence, ELISA, Western Blot, biological neutralization of proNGF. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: proNGF
Clonality: Polyclonal
Conjugation: Unconjugated
Epitope: Multiple epitopes because of the nature of the immunogen
Host: Sheep
Isotype: IgG
Reactivity: Human, Mouse, Rat
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