Anti-Orexin A Rabbit Polyclonal Antibody

Toimittaja: Biosensis
BSENR-104-100EA 302 EUR
Anti-Orexin A Rabbit Polyclonal Antibody
FUNCTION: Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity. SUBCELLULAR LOCATION: Endoplasmic reticulum; rough endoplasmic reticulum. Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses. SIMILARITY: Belongs to the orexin family.

The specificity for this antiserum has been confirmed by immunohistochemistry on rat brain and the results reflect the current literature.
Application Information:
IHC. This is a superb antiserum for immunohistochemistry on Orexin A containing neurons exhibiting intense labelling of neurons with very low back ground. A dilution of 1:1000 to 1:2000 is recommended for this application. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: Orexin A
Clonality: Polyclonal
Conjugation: Unconjugated
Epitope: Bovine Orexin A (aa: 14-33)
Host: Rabbit
Isotype: IgG
Reactivity: Rat
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