ATG10 plays a role in autophagy. It is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12-ATG5 conjugations and modificatioon of a soluble form of MAPLC3 1A, a homolog of yeast ATG8, to a membrane bound form. It is also able to directly interact either with ATG5 or ATG7.
IHC, WB and ELISA confirmed the specificity for ATG10.
Application Information:
IHC, immunofluorescence. A dilution of 1:100 to 1:1000 dilution is recommended for these applications. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: ATG10
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: C-terminal of Human ATG10
Host: Rabbit
Isotype: IgG
Reactivity: Human