APPL2 is an isoform of APPL1 with 54% identity in their protein sequences. APPL2 has a role in cell proliferation and embryonic development. Recently, it was shown that APPL2 regulates FSH signaling and acts as a negative regulator in adiponectin signaling.
Antibody is known to recognize APPL2 by Western Blotting (WB) and Immunoprecipitation (IP). A dilution of 1:1,000 is recommended for WB. A concentration of 3 µl/reaction is recommended for IP. Biosensis recommends optimal dilutions/concentrations should be determined by the end user. This antiserum is known to recognise both mouse and human APPL2.
Application Information:
Western Blotting (WB) and Immunoprecipitation (IP). A dilution between 1:2500 and 1:5000 is recommended for WB. A concentration of 3 µl/reaction is recommended for IP. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: mouse APPL2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: Mouse APPL2 protein (amino acids: 619-662)
Host: Rabbit
Isotype:
Reactivity: Mouse, Human
