Anti-beta synuclein Sheep Polyclonal Antibody

Toimittaja: Biosensis
BSENS-041-100EA 312 EUR
BSENS-041-100
Anti-beta synuclein Sheep Polyclonal Antibody
Vasta-aineet
Beta-synuclein is a non-amyloid component of senile plaques found in Alzheimer disease. It could act as a regulator of SNCA aggregation. It protects nerurons from staurosporine and 6 hydroxy dopamine -stimulated capspase activation in a p53-dependent manner. It localises to the cytoplasm and it is predominantly expressed in the brain where it is most concentrated in presynaptic nerve terminals. This protein is phosphorylated. This protein is also associated with the disease Brain iron accumulation type 1 (NBIA1).

Known to be specific for beta synuclein.
Application Information:
IHC. A dilution of 1:3000 to 1:8000 is recommended. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: beta synuclein
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: Human beta synuclein protein (aa: 108-125)
Host: Sheep
Isotype: IgG
Reactivity: Human, Rat, Rodent
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