Human recombinant furin

Toimittaja: Tonbo Biosciences
21-7106-U500EA 2880 EUR
TNBO21-7106-U500 TNBO21-7106-U010 TNBO21-7106-U002 TNBO21-7106-U100
Human recombinant furin
Furin is a member of the subtilisin-like proprotein convertase (PC) family, a part of the subtilisin superfamily of serine proteases. It is a type I membrane bound calcium-dependent protease and is expressed in tissues including liver, gut, brain and neuroendocrine. It is localised in the Golgi apparatus and functions to cleave various proproteins with a specific recognition sequence into their mature forms. Substrates are involved in various secretory pathways and include proalbumin, membrane type-1 matrix metalloproteinase, von Willebrand factor and proparathyroid hormone.
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