7-Ethyl-10-hydroxycamptothecin ≥98%
Toimittaja: Cayman Chemical
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Vaara
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CAYM15632-10EA
159
EUR
CAYM15632-10
CAYM15632-50
CAYM15632-5
7-Ethyl-10-hydroxycamptothecin ≥98%
7-Ethyl-10-hydroxycamptothecin
SN-38 is the active metabolite of irinotecan, a derivative of the alkaloid camptothecin and acts as a potent inhibitor of DNA topoisomerase I. SN-38 is a more potent topopisomerase I inhibitor and more cytotoxic to HT-29 colon cancer cells (IC50 = 8.8 nM) compared to irinotecan (IC50 >100 nM).
- SN-38 is in a form of crystalline solid
- λmax at 224, 267, 331, 368, 383 nm
Kaava:
C₂₂H₂₀N₂O₅ Storage Temperature: Pakastin |
MDL numero:
MFCD06762720 CAS-numero: 86639-52-3 UN: 2811 ADR: 6.1,III |
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