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Anti-GPR182 Rabbit Polyclonal Antibody

Toimittaja: ProSci Inc.
G Protein-Coupled Receptor L1/G10D (GPR182) has been suggested to be an Adrenomedullin Receptor. Originally cloned from rats and later from humans, L1/G10D does not to bind adrenomedullin or display functional cAMP response to adrenomedullin . The initial experimental results, which demonstrated high-affinity binding and increased levels of cAMP in COS cells that were transfected with L1/G10D and treated with adrenomedullin, could not be reproduced by other laboratories (Kapas et al. 1995). It is now known that the functional adrenomedullin receptor is a heterodimeric complex composed of calcitonin receptor-like receptor (CRLR) and receptor activity modifying proteins (RAMPs) (McLatchie et al. 1998). L1/G10D therefore should be considered an Orphan A receptor.

GPR182 antibody can be used in ELISA, and immunohistochemistry starting at 10 μg/mL.

PBS, 0.1% sodium azide.

PBS, 0.1% sodium azide.

Aliquot and store at -80°C. Avoid multiple freeze-thaw cycles.

Antigen: GPR182
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Reactivity: Human

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Pistosyvyys Pak. VWR-tuoteluettelon nro Määrä
50 µg 50 µG PRSI48-233
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Antigeenin symboli GPR182
Antigeenin nimi G Protein-coupled Receptor 182
Reaktiivisuus Human
Konjugaatio Unconjugated
Klonaalisuus Polyclonal
Isäntä Rabbit
ImmunoChemistry Yes
Antigen synonyms G10D, AMR, gamrh, hrhAMR, ADMR, 7TMR, AM-R
Immunogeeni GPR182 antibody was raised against a peptide located in the C-Terminal domain of GPR182 (Human).
Form Liquid
Testatut aplikaatiot Immunoaffinity Chromatography
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