Human recombinant Myostatin (from E. coli)

Toimittaja: Shenandoah Biotechnology
SHBT100-22-500UGEA 3340 EUR
SHBT100-22-500UG SHBT100-22-1MG SHBT100-22-100UG SHBT100-22-10UG
Human recombinant Myostatin (from E. coli)
Proteiinit
Myostatin is an essential regulator of skeletal muscle mass and cardiac muscle development and function. It is also known as GDF-8, is a conserved member of the TGF-beta superfamily. Myostatin is a secreted protein that negatively regulates skeletal muscle growth by determining muscle fiber number and size.

  • Produced from genetically modified E. coil
  • Dimeric protein, containing 109/218 amino acids

Myostatin binds one of the two activin type II receptors (ACTRIIA or ACTRIIB) to activate SMAD signaling. Myostatin also activates MAPK signaling through TAK1-MKK6 and Ras pathways. Inhibition of myostatin increases muscle mass in a number of human disease animal models, such as muscular dystrophy.

Toimitustiedot: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.

Varoitus: This product is for research use only and is not for use in humans.
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