DTME (dithio-bis-maleimidoethane), Pierce™

Toimittaja: Thermo Fisher Scientific

Synonyms: DTME

PIER22335EA 370 EUR
DTME (dithio-bis-maleimidoethane), Pierce™
DTME (dithio-bis-maleimidoethane)

Thermo Scientific Pierce DTME is a mid-length, maleimide crosslinker for reversible covalent conjugation between sulfhydryl groups (e.g., protein or peptide cysteines) by reduction of the disulfide bond in the center of the spacer arm.

  • Reactive groups: maleimide (both ends)
  • Reactive towards: sulfhydryl groups
  • Long (13.3A), cleavable, sulfhydryl-to-sulfhydryl crosslinker, composed of maleimide groups and 11-atom disulfide spacer arm
  • Water-insoluble—dissolve first in DMF or DMSO, then add to aqueous reaction buffers
  • Cleavable by reduction of disulfide spacer arm with DTT, TCEP or other reducing agent

Varoitus: For Research Use Only. Not for use in diagnostic procedures.

Kaava: C₁₂H₁₂N₂O₄S₂
MW: 312,36 g/mol
Storage Temperature: Jääkaappi
MDL numero: MFCD01863385
CAS-numero: 71865-37-7

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Product Line Pierce™
Labeling Method Chemical Labeling
Crosslinker Type Homobifunctional
Reactive Moiety Maleimide
Spacer Cleavable, Long
Form Solid
Quantity 50 mg
Type Crosslinker
Solubility DMF, DMSO
Spacer Arm 13.3 Å

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